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There have been no experience to date with the usage of METROGEL-VAGINAL in Expecting clients. Metronidazole crosses the placental barrier and enters the fetal circulation quickly. No fetotoxicity or teratogenicity was noticed when metronidazole was administered orally to Expecting mice at six times the advisable human dose (determined by mg/m2); on the other hand, in only one little analyze in which the drug was administered intraperitoneally, some intrauterine deaths have been noticed. The connection of these conclusions to the drug is unfamiliar.
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, and Mycoplasma jnetoto hominis, has not been outlined. Even so, metronidazole is an antimicrobial agent Energetic in vitro against most strains of the following organisms that have been claimed being affiliated with bacterial jnetoto vaginosis:
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Disulfiram-like reaction to Liquor has actually been reported with oral metronidazole, thus the potential of such a reaction occurring although on metronidazole vaginal gel therapy cannot be excluded.
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